What is a significant advantage of using gold nanoparticles in drug delivery?

The significant advantage of using gold nanoparticles in drug delivery lies in their enhanced bioavailability of drugs. Gold nanoparticles can improve the solubility, stability, and absorbability of a drug, allowing for better therapeutic effects. Their surface can be modified to enhance interactions with biological systems, facilitating targeted delivery to specific cells or tissues. This targeted approach can lead to increased effectiveness of the drugs while reducing side effects, as more of the drug reaches its intended site of action.

In the context of drug delivery systems, increasing bioavailability is crucial because it directly influences how much of the administered drug reaches the systemic circulation and, ultimately, its therapeutic target. The small size and favorable surface chemistry of gold nanoparticles enable them to navigate biological barriers effectively, making them highly advantageous for delivering various therapeutic agents, including anticancer drugs and nucleic acids.